Memory Support
Cognition & Memory Supplements
Klaire Labs/SFI Health
Codeage
Introductory Note
This protocol represents an aggressive, comprehensive approach to memory support and cognitive deficits.
It draws on a wide range of nutrients, antioxidants, mitochondrial enhancers, and adaptogens, each selected for their evidence-based roles in protecting brain cells, boosting neurotransmitter activity, and sustaining mental clarity. While many of these supplements can benefit healthy individuals, this strategy is especially geared toward those seeking more intensive support for age-related memory decline, brain fog, or other cognitive challenges. For people who only need a mild mental boost, NeuroThera may be sufficient.
Key Supplements for Brain Health and Cognitive Protection
Core nutrients protect neurons and sharpen memory.
Nutritional supplements for memory and cognition play a crucial role in supporting brain health, enhancing neurotransmitter function, and protecting against cognitive decline. Omega-3 fatty acids, particularly DHA, are essential for neuronal function, helping to maintain brain structure and reduce inflammation. Antioxidants like resveratrol and CoQ10 combat oxidative stress, which contributes to age-related cognitive decline. Phosphatidylserine, a key component of cell membranes, supports communication between brain cells, promoting memory retention and mental clarity.
N-Acetyl-Cysteine (NAC): NAC is a powerful antioxidant and precursor to glutathione, the brain’s master detoxifier. It protects neurons from oxidative stress and inflammation, both strongly linked to cognitive decline. Clinical research suggests NAC may improve symptoms in conditions such as Alzheimer’s, traumatic brain injury, and psychiatric disorders by restoring glutamate balance and protecting brain cells. Adding NAC can enhance overall resilience against memory loss and support focus under stress.
Alpha-Lipoic Acid (ALA): ALA is a unique antioxidant that crosses the blood–brain barrier and works in both fat- and water-soluble environments. It helps regenerate other antioxidants such as vitamin C, vitamin E, and glutathione, amplifying their neuroprotective effects. ALA supports mitochondrial energy metabolism in brain cells, which is critical for memory and learning. It has also been studied in diabetes-related cognitive impairment, showing improvements in mental performance.
Polyphenols and Fruit-Based Neuroprotective Compounds
Plant compounds fuel brain circulation and protect neurons.
Polyphenols from fruits are particularly beneficial for brain health and anti-aging. Flavonoids found in berries, quercetin in apples, and catechins in grapes have neuroprotective effects, reducing inflammation and improving blood circulation to the brain. These compounds help enhance cognitive function by supporting neurogenesis, the growth of new brain cells, and protecting existing neurons from oxidative damage. High-polyphenol fruits like blueberries, pomegranates, and citrus fruits have been linked to improved memory and learning ability.
Neurotransmitter Precursors and Cognitive Enhancement
Precursors boost focus, clarity, and mental energy.
Neurotransmitter precursors play a critical role in cognitive function by supporting the production of key brain chemicals. CDP-choline (citicoline) enhances acetylcholine levels, which are essential for memory, attention, and overall brain function. Acetyl-L-carnitine (ALCAR) supports mitochondrial energy production and helps transport fatty acids into brain cells, improving mental clarity and reducing brain fog. L-tyrosine serves as a precursor to dopamine, norepinephrine, and epinephrine, neurotransmitters involved in focus, motivation, and stress resilience. Supplementing with these compounds can enhance cognitive performance, especially under conditions of mental fatigue or stress.
Creatine Monohydrate: Best known for muscle energy, creatine also serves as a quick-acting energy buffer for brain cells. Supplementation has been shown to reduce mental fatigue and improve short-term memory, particularly under stress or sleep deprivation. For older adults, creatine may help maintain mental energy and processing speed by supporting ATP availability in neurons.
Adaptogens and Nutrients for Mental Resilience
Adaptogens strengthen stress response and memory retention.
Adaptogenic herbs like ashwagandha and Rhodiola rosea help the body manage stress, a key factor in cognitive decline. Bacopa monnieri has been shown to enhance memory, processing speed, and overall cognitive resilience. Additionally, essential nutrients like B vitamins, magnesium, and zinc contribute to neurotransmitter production, further optimizing brain function.
Holistic Approach to Sustaining Cognitive Function
Lifestyle and supplements together preserve brain power.
A combination of these supplements, along with a balanced diet, regular exercise, and stress management, supports long-term cognitive performance and overall brain health. Adding practices such as mindfulness meditation, learning new skills, and maintaining social connections further strengthens cognitive resilience. Together, these strategies create a comprehensive approach to sustaining memory, focus, and mental clarity across the lifespan.
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- SPOTLIGHT -
NeuroThera for Cognition & Memory
Key nutrients that fuel focus, memory & long-term brain health.
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Alpha-GPC → Boost acetylcholine for sharper memory & learning.
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Acetyl-L-Carnitine → Fuels brain energy & protects neurons from stress.
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L-Tyrosine → Builds dopamine & norepinephrine for focus & motivation.
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Glutamine & L-Pyroglutamic Acid → Support balanced brain signaling (calm + alert).
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DMAE → Enhances attention & mental drive.
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Ashwagandha & Eleuthero → Adaptogens that lower stress & fight mental fatigue.
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Blueberry & Ginkgo → Improve circulation & protect brain cells with antioxidants.
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Phosphatidylserine → Keeps brain cell membranes healthy for clear signaling.
Why It Works Together:
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Fuels key neurotransmitters (memory, mood, focus)
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Boosts brain energy & resilience
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Protects neurons against stress & aging
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Supports both quick clarity & long-term cognition